I've been playing this game all week and just recently ran into a red boss that absorbs almost all damage so I cap at 9k per hit and deals damage well over my HP total. I have a very strong blue team with 150% burst gem dmg, 40% blue damage, and 25% lawful damage. I changed all reds to heart gems, then all heart gems to blue burst and my final outcome was about 250k/hit, doing double since it's blue against red. What should have been a ridiculous overkill doing 3,000,000+ dmg didn't even scratch him because he absorbed all but 45k of it. Is there some trick to downing these guys? Or is it just some cruel endurance battle against a guy that 1shots you?